AFN-1252(Debio 1452) - Names and Identifiers
Name | AFN-1252
|
Synonyms | CS-2098 AFN-1252 Debio-1452 AFN-1252, API-1252 AFN-1252(Debio 1452) (E)-N-Methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide (E)-3-(1,2,3,4-tetrahydro-2-oxo-1,8-naphthyridin-6-yl)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)acrylamide (2E)-N-Methyl-N-[(3-methyl-1-benzofuran-2-yl)methyl]-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide
|
CAS | 620175-39-5
|
AFN-1252(Debio 1452) - Physico-chemical Properties
Molecular Formula | C22H21N3O3
|
Molar Mass | 375.42 |
Density | 1.28±0.1 g/cm3(Predicted) |
Boling Point | 601.2±65.0 °C(Predicted) |
Solubility | DMSO: 5.8 mg/mL(Need ultrasonic) |
pKa | 3.60±0.20(Predicted) |
Storage Condition | 2-8°C |
AFN-1252(Debio 1452) - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 2.664 ml | 13.318 ml | 26.637 ml |
5 mM | 0.533 ml | 2.664 ml | 5.327 ml |
10 mM | 0.266 ml | 1.332 ml | 2.664 ml |
5 mM | 0.053 ml | 0.266 ml | 0.533 ml |
Last Update:2024-01-02 23:10:35
AFN-1252(Debio 1452) - Reference Information
biological activity | AFN-1252(Debio 1452) is a highly potent inhibitor of FabI, which can inhibit Staphylococcus aureus. |
Last Update:2024-04-10 22:30:50